EnduNAD review: ingredients, doses and who it is (not) for
EnduNAD
- 250 mg niacinamide (vitamin B3) as the main NAD+ precursor
- Plus B6, L-tryptophan and five plant extracts
- 2 capsules a day, 60 capsules per bottle (30 days)
- Vegan and made in Europe, according to the seller
Affiliate link: we earn a commission if you buy through this link, at no extra cost to you.
What is EnduNAD?
EnduNAD markets itself as a "multi-ingredient NAD+ booster". Instead of a single precursor such as NMN or nicotinamide riboside, it combines vitamin B3 with a range of plant extracts and other compounds. The idea is to give your body the raw materials to make NAD+ itself, plus ingredients the maker says support that process.
New to NAD+? Start with what NAD+ is and our guide to NAD supplements. Worried about safety? See NAD supplement side effects.
Ingredients and doses
This is what the manufacturer lists per daily serving of 2 capsules. The last column is our own calculation.
| Ingredient | Per serving | What that means |
|---|---|---|
| Niacin (as niacinamide) | 250 mg (1,563% DV) | NAD+ precursor. Over 7 times the US upper limit of 35 mg |
| Fenugreek seed extract (2% trigonelline) | 300 mg | About 6 mg trigonelline. Standalone trigonelline products use around 250 mg |
| L-tryptophan | 200 mg | Amino acid the body can also convert into NAD+ |
| Chamomile flower extract (5% apigenin) | 150 mg | About 7.5 mg apigenin |
| Green tea leaf extract (40% EGCG) | 150 mg | About 60 mg EGCG |
| Grape extract (2% resveratrol) | 50 mg | About 1 mg resveratrol. Studies typically use 150 mg or more |
| Alpha-lipoic acid | 50 mg | Antioxidant |
| Vitamin B6 | 2.8 mg (165% DV) | Vitamin |
| Black pepper extract (BioPerine®) | 2 mg | Added to improve absorption |
The niacinamide dose: 250 mg vs the 35 mg upper limit
The US Tolerable Upper Intake Level for supplemental niacin is 35 mg a day for adults. That limit was set mainly to prevent the flushing caused by nicotinic acid, the other form of B3. Niacinamide does not cause flushing, and adverse effects such as liver problems have been reported at doses far higher than 250 mg. Many single-ingredient niacinamide supplements in US stores also contain 250 to 500 mg per capsule.
Still, 250 mg a day is a pharmacological dose, not a nutritional one. Taking it long term without telling your doctor is not a good idea, especially if you have liver disease or take other medication.
What can you realistically expect?
The evidence-backed part of EnduNAD is vitamin B3 and B6:
- Niacin supports normal energy metabolism.*
- Niacin and vitamin B6 help the body convert food into energy.*
- Niacinamide is a well-documented building block for NAD+.
If you already get enough niacin from food, which most Americans do, a supplement is unlikely to give you a noticeable energy boost. And if you are tired all the time for no obvious reason, see your doctor first.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
What the seller promises, and what we think
The official sales page makes much bigger promises: stronger muscles, weight control, heart and brain support, stronger immunity, DNA repair and slower aging. It also states that NAD+ levels drop by 65% between ages 30 and 70, and that the niacin in the formula helps lower cholesterol.
We are skeptical:
- No source for the 65%. Recent reviews show that an age-related drop in NAD+ has only been measured consistently in a limited number of human studies.
- No research on the product itself. The claims are borrowed from studies on individual ingredients, often in animals and at much higher doses.
- The cholesterol claim doesn't fit the formula. Only nicotinic acid affects cholesterol, at prescription doses of 1,000 mg or more. EnduNAD uses niacinamide, which has no effect on cholesterol. See niacinamide vs niacin.
- Small doses of the "extras". Trigonelline (about 6 mg) and resveratrol (about 1 mg) are present in amounts far below what research has used.
That doesn't make EnduNAD a bad product. It does help keep your expectations realistic.
EnduNAD vs NMN and NR
NMN and nicotinamide riboside (NR) have more direct human data showing they raise NAD+ levels in blood. Niacinamide also raises NAD+, is much cheaper per gram and has a long safety record, but it has been studied less specifically as a "NAD booster". EnduNAD is essentially a niacinamide product with extras. If raising NAD+ with the best-studied precursor is your main goal, NR is the more direct choice. If you want an affordable, flush-free B3 formula with a few supporting ingredients, EnduNAD fits that brief. See how it compares in our best NAD supplement picks.
Who is EnduNAD for, and who should skip it?
May suit
- Adults who want a flush-free vitamin B3 based NAD+ formula
- People focused on healthy aging who prefer a combination product
- Anyone who needs a vegan product
Skip it or ask your doctor first
- Pregnant or breastfeeding women
- People on antidepressants (L-tryptophan), blood thinners or other medication
- People with liver disease
- Children and teenagers
- Anyone with ongoing fatigue that a doctor hasn't looked into
Pros and cons
Pros
- Transparent label with the dose of every ingredient
- Niacinamide, so no niacin flush
- Simple routine: 2 capsules a day
Cons
- Sales page promises more than the evidence supports
- No independent research on the product
- Niacinamide dose well above the US upper limit
- Trigonelline and resveratrol doses are small
- Only sold online through the official site
EnduNAD reviews and customer experiences
Search for EnduNAD reviews and you'll mostly find glowing stories. Look at who publishes them: many review sites earn a commission on sales, just like we do. That is why we don't publish made-up or copied testimonials. Have you used EnduNAD yourself? We'd like to hear your honest experience, positive or negative.
Where to buy EnduNAD
EnduNAD is only sold online through the official website, so ordering there is the way to be sure you get the genuine product. The site currently advertises up to 20% off, and multi-bottle bundles lower the price per bottle, which makes sense if you plan to try it for a couple of months. Check the delivery time and return conditions on the order page.
Affiliate link: we earn a commission if you buy through this link, at no extra cost to you.
Frequently asked questions
What is EnduNAD?
EnduNAD is a capsule supplement that combines niacinamide (vitamin B3), a NAD+ precursor, with vitamin B6, L-tryptophan and extracts of fenugreek, green tea, chamomile and grape, plus alpha-lipoic acid and black pepper extract. It contains no NMN or nicotinamide riboside.
Does EnduNAD work?
Its niacinamide supports normal energy metabolism, because your body uses vitamin B3 to make NAD+. There are no published studies on EnduNAD as a product, so claims about slowing aging, DNA repair or weight control are not backed by evidence for this formula.
How do you take EnduNAD?
According to the seller, take 2 capsules a day with about 10 oz (300 ml) of water, not on an empty stomach. One bottle holds 60 capsules, a 30-day supply.
Does EnduNAD have side effects?
The seller lists no specific side effects. It does contain 250 mg niacinamide a day, well above the US upper limit of 35 mg for supplemental niacin, plus 200 mg L-tryptophan. Talk to your doctor first if you take antidepressants, blood thinners or other medication, have liver disease, or are pregnant or breastfeeding.
Is EnduNAD the same as an NMN supplement?
No. EnduNAD relies on niacinamide as its main NAD+ precursor. NMN and nicotinamide riboside are different precursors with more direct human data on raising NAD+ levels, but they are also more expensive.
Where can you buy EnduNAD?
EnduNAD is sold online through the official website. It is not available on Amazon or in US stores as far as we know. Check the current price, shipping time and return terms on the official site before you order.
Sources
- EnduNAD, official product information (ingredients, directions, terms).
- NIH Office of Dietary Supplements: Niacin fact sheet for health professionals.
- Vinten et al. (2025). NAD+ precursor supplementation in human ageing. Nature Metabolism.
- Peluso et al. (2021). Age-Dependent Decline of NAD+. Nutrients.
- Hwang and Song (2020). Possible Adverse Effects of High-Dose Nicotinamide: Mechanisms and Safety Assessment. Biomolecules.
Read next
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EGCG benefits: what green tea's key compound can and can't do
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L-tryptophan benefits: sleep, mood and NAD+, plus the safety history you should know
L-tryptophan benefits for sleep, mood and NAD+ production, what the evidence shows, food sources, doses, the 1989 EMS outbreak and drug interactions.
This review is general information and not medical advice. This page contains affiliate links.