Articles and guides

Plain-English guides on NAD+, its precursors and vitamin B3, with what the research does and does not show.

Five plain supplement bottles without labels lined up on a light oak table next to a dish of capsules

Best NAD supplement in 2026: honest picks by goal (and the label problem most lists ignore)

The best NAD supplement depends on your goal and budget. Honest picks for NR, combination and niacinamide formulas, plus why most NAD+ labels fail lab tests.

Glass teapot of green tea and a cup on a cream table beside fresh green tea leaves in soft daylight

EGCG benefits: what green tea's key compound can and can't do

EGCG benefits explained: what green tea's main catechin does for metabolism, heart and cells, what the evidence shows, and the 800 mg liver safety threshold.

Woman in her fifties sitting in bed in the evening with a cup of tea and a book, warm soft light

L-tryptophan benefits: sleep, mood and NAD+, plus the safety history you should know

L-tryptophan benefits for sleep, mood and NAD+ production, what the evidence shows, food sources, doses, the 1989 EMS outbreak and drug interactions.

Woman in her early fifties resting on a sofa with a cup of tea in soft afternoon light, looking calm but tired

Menopause fatigue: why you're so tired, and what actually helps

Menopause fatigue is common, but it isn't always hormones. The main causes, which tests to ask your doctor for, and what helps, including where supplements fit.

Man and woman in their fifties walking briskly on a park path on a bright morning

NAD+ benefits: what's proven, what's promising, and what's hype

NAD+ benefits graded by evidence: energy, aging, muscle, metabolism, brain and skin. What human studies show, what is animal data, and what is hype.

Man in his fifties looking skeptically at a small unlabeled spray bottle and a box in a bright bathroom

NAD+ patches, nasal sprays and liposomal NAD: do they work?

NAD patches, nasal sprays and liposomal NAD promise better absorption. What the evidence shows for each, how they compare with oral precursors, and costs.

Glass of water and a small dish of white capsules on a kitchen table, with a calm woman in a sage-green sweater sitting behind it

NAD+ pills vs injections vs IV: what actually works, and what it costs

NAD pills vs injections and IV drips: how each gets into your body, what the evidence shows, side effects and cost per month. An honest comparison.

Woman in her fifties sitting at a kitchen table reading the warning section on a supplement label

NAD supplement side effects: what to expect from each type (and who should avoid them)

NAD supplement side effects depend on the type: niacin, niacinamide, NR, NMN or IV NAD+. Common reactions, rare risks, drug interactions and who should avoid.

Two small ceramic dishes with white capsules and white powder on a light wooden table near a window

NAD vs NMN: what's the difference, and which one actually raises NAD+?

NAD vs NMN explained: NAD+ is the molecule your cells use, NMN is a precursor. Absorption, human evidence, US legal status, safety and which makes sense.

Man in his fifties in a kitchen touching his flushed red cheek

Niacin flush: why it happens, how long it lasts, and how to prevent it

Niacin flush: why vitamin B3 makes your skin red, hot and itchy, how long it lasts, when to worry, and 6 ways to prevent it, including no-flush forms.

Two small glass dishes with white capsules and tablets on a light kitchen counter, a woman reading a supplement label in the background

Niacinamide vs niacin: what's the difference, and which one do you need?

Niacinamide vs niacin: both are vitamin B3, but only niacin flushes and affects cholesterol. Doses, safety, NAD+ and which form fits your goal.

Man in his fifties comparing two plain white supplement bottles in a bright kitchen

Nicotinamide vs niacinamide: same molecule, different name (and the names that really differ)

Nicotinamide vs niacinamide: one molecule, two names. Why both exist, how to read labels, and how they differ from niacin, NR and NMN. Doses and safety.

Couple in their fifties at a kitchen table comparing two plain supplement bottles over breakfast

NMN vs NR: which NAD+ precursor has the better evidence?

NMN vs NR compared: how each turns into NAD+, what human trials show, safety, US legal status and cost. Plus the cheaper niacinamide alternative.

Cup of coffee next to a small bowl of fenugreek seeds on a light wooden table in morning light

Trigonelline: the coffee compound studied as a new NAD+ precursor

Trigonelline, a niacin-related compound in coffee and fenugreek, is a newly identified NAD+ precursor. What research shows, food sources, doses and safety.

Woman in her fifties stretching in a sunlit living room in the morning

What is NAD+? What it does, why it drops, and how to support it

What is NAD+? The coenzyme in every cell that turns food into energy and fuels DNA repair. What it does, why levels may drop with age, and what helps.

Review

EnduNAD review

Ingredients, doses, what to realistically expect and who should skip it.